Comparison Among Methods of Retinopathy Assessment (CAMRA) Study

Ryan, M E and Rajalakshmi, R and Prathiba, V and Anjana, R M and Ranjani, H and Narayan, K M V and Olsen, T W and Mohan, V and Ward, L A and Lynn, M J and Hendrick, A M (2015) Comparison Among Methods of Retinopathy Assessment (CAMRA) Study. Ophthalmology, 122 (10). p. 2038. ISSN 01616420



Purpose: We compared smartphone fundus photography, nonmydriatic fundus photography, and 7-field mydriatic fundus photography for their abilities to detect and grade diabetic retinopathy (DR). Design: This was a prospective, comparative study of 3 photography modalities. Participants: Diabetic patients (n ¼ 300) were recruited at the ophthalmology clinic of a tertiary diabetes care center in Chennai, India. Methods: Patients underwent photography by all 3 modalities, and photographs were evaluated by 2 retina specialists. Main Outcome Measures: The sensitivity and specificity in the detection of DR for both smartphone and nonmydriatic photography were determined by comparison with the standard method, 7-field mydriatic fundus photography. Results: The sensitivity and specificity of smartphone fundus photography, compared with 7-field mydriatic fundus photography, for the detection of any DR were 50% (95% confidence interval [CI], 43e56) and 94% (95% CI, 92e97), respectively, and of nonmydriatic fundus photography were 81% (95% CI, 75e86) and 94% (95% CI, 92e96%), respectively. The sensitivity and specificity of smartphone fundus photography for the detection of vision-threatening DR were 59% (95% CI, 46e72) and 100% (95% CI, 99e100), respectively, and of nonmydriatic fundus photography were 54% (95% CI, 40e67) and 99% (95% CI, 98e100), respectively. Conclusions: Smartphone and nonmydriatic fundus photography are each able to detect DR and sightthreatening disease. However, the nonmydriatic camera is more sensitive at detecting DR than the smartphone. At this time, the benefits of the smartphone (connectivity, portability, and reduced cost) are not offset by the lack of sufficient sensitivity for detection of DR in most clinical circumstances. Ophthalmology 2015;122:2038- 2043 ª 2015 by the American Academy of Ophthalmology.

Item Type:Article
Official URL/DOI:
Uncontrolled Keywords:CAMRA; Retinopathy
Subjects:Diabetology > Retino Diabetology
Divisions:Department of Opthalmology
ID Code:938
Deposited By:surendar radha
Deposited On:25 Sep 2015 12:22
Last Modified:25 Sep 2015 12:22

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