Balasubramanyam, M (2014) Metformin: Nature’s Gift that Keeps on Giving More. Journal of Obesity and Metabolic Research, 1 (2). p. 118.
Despite many different drugs being available for type 2 diabetes, metformin remains a cornerstone in the management of diabetes. In a consensus statement, the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) recommend metformin as the first step in the treatment type 2 diabetes, in the absence of drug contraindications. Thus, worldwide, metformin is now the unanimous first‑line glucose‑lowering agent. While several recent antidiabetic drugs have been under the cloud, some being withdrawn, others asked to give warnings in labels and a few still under strict Food and Drug Administration (FDA) scrutiny, metformin, a time‑tested drug, has surpassed the hurdles and become the most prescribed medicine in diabetes and other conditions of insulin resistance. Why is there now a “metformin wave” everywhere? Here, we will discuss this “metformin paradox” of an old wine in a new bottle.
|Subjects:||Biochemistry,Cell and Molecular Signalling|
|Divisions:||Department of Advanced Research Biochemistry|
|Deposited By:||surendar radha|
|Deposited On:||06 Nov 2014 15:52|
|Last Modified:||06 Nov 2014 15:52|
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