Prevalence of dyslipidemia in urban and rural India: the ICMR-INDIAB study.

Joshi, S R and Anjana, R M and Deepa, M and Pradeepa, R and Bhansali, A and Dhandania, V and Joshi, P P and Unnikrishnan, R and Nirmal, E and Subashini, R and Madhu, S V and Rao, P V and Das, A K and Kaur, T and Shukla, D K and Mohan, V (2014) Prevalence of dyslipidemia in urban and rural India: the ICMR-INDIAB study. PloS one, 9 (5). e96808. ISSN 1932-6203



AIM: To study the pattern and prevalence of dyslipidemia in a large representative sample of four selected regions in India. METHODS: Phase I of the Indian Council of Medical Research-India Diabetes (ICMR-INDIAB) study was conducted in a representative population of three states of India [Tamil Nadu, Maharashtra and Jharkhand] and one Union Territory [Chandigarh], and covered a population of 213 million people using stratified multistage sampling design to recruit individuals ≥20 years of age. All the study subjects (n = 16,607) underwent anthropometric measurements and oral glucose tolerance tests were done using capillary blood (except in self-reported diabetes). In addition, in every 5th subject (n = 2042), a fasting venous sample was collected and assayed for lipids. Dyslipidemia was diagnosed using National Cholesterol Education Programme (NCEP) guidelines. RESULTS: Of the subjects studied, 13.9% had hypercholesterolemia, 29.5% had hypertriglyceridemia, 72.3% had low HDL-C, 11.8% had high LDL-C levels and 79% had abnormalities in one of the lipid parameters. Regional disparity exists with the highest rates of hypercholesterolemia observed in Tamilnadu (18.3%), highest rates of hypertriglyceridemia in Chandigarh (38.6%), highest rates of low HDL-C in Jharkhand (76.8%) and highest rates of high LDL-C in Tamilnadu (15.8%). Except for low HDL-C and in the state of Maharashtra, in all other states, urban residents had the highest prevalence of lipid abnormalities compared to rural residents. Low HDL-C was the most common lipid abnormality (72.3%) in all the four regions studied; in 44.9% of subjects, it was present as an isolated abnormality. Common significant risk factors for dyslipidemia included obesity, diabetes, and dysglycemia. CONCLUSION: The prevalence of dyslipidemia is very high in India, which calls for urgent lifestyle intervention strategies to prevent and manage this important cardiovascular risk factor

Item Type:Article
Official URL/DOI:
Uncontrolled Keywords:dyslipidemia, ICMR-INDIAB study,
Subjects:Diabetes > Diabetes in India
Diabetes > Diabetes Research
Divisions:Department of Epidemiology
Department of Diabetology
Department of Advanced Research Biochemistry
ID Code:816
Deposited By:surendar radha
Deposited On:25 Jul 2014 12:06
Last Modified:25 Jul 2014 12:06

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