Improving diabetes care: Multi-component cardiovascular disease risk reduction strategies for people with diabetes in South Asia—The CARRS Multi-center Translation Trial

Shah, S and Singh, K and Ali, M K and Mohan, V and Kadir, M M and Unnikrishnan, A G and Sahay, R K and Varthakavi, P and Dharmalingam, M and Viswanathan, Vijay and Masood, Q and Bantwal, G and Khadgawat, R and Desai, A and Sethi, B K and Shivashankar, R and Ajay, V S and Reddy, K S and Narayan, K M V and Prabhakaran, D and Tandon, N (2012) Improving diabetes care: Multi-component cardiovascular disease risk reduction strategies for people with diabetes in South Asia—The CARRS Multi-center Translation Trial. Diabetes Research and Clinical Practice . ISSN 01688227 (In Press)

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Abstract

Abstract Aims Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in people with diabetes in South Asia. The CARRS Translation Trial tests the effectiveness, cost-effectiveness, and sustainability of a clinic-based multi-component CVD risk reduction intervention among people with diabetes in India and Pakistan. Methods We randomly assigned 1146 adults with diabetes recruited from 10 urban clinic sites, to receive usual care by physicians or to receive an integrated multi-component CVD risk reduction intervention. The intervention involves electronic health record management, decision-support prompts to the healthcare team, and the support of a care coordinator to actively facilitate patient and provider adherence to evidence-based guidelines. The primary outcome is a composite of multiple CVD risk factor control (blood glucose and either blood pressure or cholesterol, or all three). Other outcomes include control of the individual CVD risk factors, process and patient-centered measures, cost-effectiveness, and acceptability/feasibility. Conclusion The CARRS Translation Trial tests a low-cost diabetes care delivery model in urban South Asia to achieve comprehensive cardio-metabolic disease case-management of high-risk patients (clinicaltrials.gov number: NCT01212328). Keywords: Diabetes, Cardiovascular risk, South Asia, Translation research, Healthcare delivery

Item Type:Article
Official URL/DOI:http://dx.doi.org/10.1016/j.diabres.2012.09.023
Uncontrolled Keywords:Diabetes; Cardiovascular risk; South Asia; Translation research; Healthcare delivery
Subjects:Diabetes Epidemiology
Diabetes
Divisions:Department of Epidemiology
Department of Diabetology
ID Code:640
Deposited By:INVALID USER
Deposited On:29 Nov 2012 14:36
Last Modified:29 Nov 2012 14:36

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