Pancreatic beta-cell function in tropical pancreatic diabetes.

Mohan, V and Snehalatha, C and Ramachandran, A and Jayashree, R and Viswanathan, M (1983) Pancreatic beta-cell function in tropical pancreatic diabetes. Metabolism: clinical and experimental, 32 (12). pp. 1091-2. ISSN 0026-0495

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Individuals with tropical pancreatic diabetes (TPD) have features of malnutrition and insulin-dependent diabetes but do not exhibit ketosis on withdrawal of insulin. Fasting and postglucose C-peptide responses were assessed in TPD and compared with noninsulin-dependent (NIDDM), insulin-dependent (IDDM), and control groups, matched for body weight. The C-peptide concentrations were lower in TPD in comparison with the controls and NIDDM patients but were significantly higher than in classical IDDM. It is likely that the higher C-peptide is responsible for the ketosis resistance in these patients.

Item Type:Article
Official URL/DOI:
Uncontrolled Keywords:Pancreatic;beta-cell;pancreatic diabetes
Subjects:Genetics and Diabetes
Diabetology > Pancreatic Diabetes
Divisions:Neonatal Diabetes
Department of Diabetology
ID Code:421
Deposited On:06 Jan 2010 10:31
Last Modified:06 Jan 2010 10:31

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