Increased LDL cholesterol in non-insulin-dependent diabetics with maculopathy.

Mohan, R and Mohan, V and Susheela, L and Ramachandran, A and Viswanathan, M (1984) Increased LDL cholesterol in non-insulin-dependent diabetics with maculopathy. Acta diabetologica latina, 21 (1). pp. 85-9. ISSN 0001-5563



Serum cholesterol and its various lipoprotein fractions and triglycerides were measured in 50 non-insulin-dependent diabetic patients, 25 without retinopathy (group A) and 25 with diabetic maculopathy (group B) initially before control of diabetes, and again, after achieving good metabolic control. The lipid parameters were also estimated in 25 healthy non-diabetic subjects. The groups were well matched for sex, age, duration of diabetes and body weight. Mean serum total cholesterol and LDL cholesterol levels were significantly higher in group B when compared to group A, before and after achieving good metabolic control of diabetes (p less than 0.001). Mean total/HDL cholesterol and mean LDL/HDL cholesterol ratios were also significantly increased in group B as compared to group A (p less than 0.01) both before and after good diabetic control in these patients. Mean serum HDL and VLDL cholesterol and triglyceride concentrations were similar in groups A and B. The mean serum lipid concentrations in the diabetic patients without retinopathy (group A) were comparable to those of non-diabetic subjects.

Item Type:Article
Official URL/DOI:
Uncontrolled Keywords:LDL;cholesterol;non-insulin-dependent diabetics;maculopathy
Subjects:Genetics and Diabetes
Divisions:Neonatal Diabetes
Department of Diabetology
ID Code:415
Deposited On:06 Jan 2010 09:18
Last Modified:06 Jan 2010 09:18

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