Familial aggregation in tropical fibrocalculous pancreatic diabetes.

Mohan, V and Chari, S T and Hitman, G A and Suresh, S and Madanagopalan, N and Ramachandran, A and Viswanathan, M (1989) Familial aggregation in tropical fibrocalculous pancreatic diabetes. Pancreas, 4 (6). pp. 690-3. ISSN 0885-3177

Restricted to MDRF users only. Others may ->



There is very little information on the genetic factors associated with fibrocalculous pancreatic diabetes (FCPD). Ninety-eight first-degree relatives of FCPD patients were subjected to detailed studies, which included glucose tolerance tests, x-ray films of the abdomen, ultrasonography, and studies of exocrine pancreatic function. The study shows that there is a familial aggregation of FCPD with evidence of vertical transmission of the disease from parent to offspring in some families. Routine screening of families of FCPD probands helped to pick up cases in the stage of impaired glucose tolerance. There is heterogeneity in FCPD with respect to familial factors. Some families show marked familial aggregation of FCPD while in others the disease occurs either sporadically or in association with other family members who have abnormal glucose handling.

Item Type:Article
Official URL/DOI:http://journals.lww.com/pancreasjournal/pages/defa...
Uncontrolled Keywords:diabetes;fibrocalculous pancreatic diabetes.
Subjects:Genetics and Diabetes
Diabetology > Pancreatic Diabetes
Divisions:Neonatal Diabetes
Department of Diabetology
ID Code:349
Deposited On:28 Dec 2009 09:43
Last Modified:28 Dec 2009 09:43
Related URLs:

Repository Staff Only: item control page