Oxidative stress and the development of diabetic complications--antioxidants and lipid peroxidation in erythrocytes and cell membrane.

Parthiban, A and Vijayalingam, S and Shanmugasundaram, K R and Mohan, R (1995) Oxidative stress and the development of diabetic complications--antioxidants and lipid peroxidation in erythrocytes and cell membrane. Cell biology international, 19 (12). pp. 987-93. ISSN 1065-6995

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Abstract

Erythrocytes isolated from 131 cases of Non-Insulin Dependent Diabetes Mellitus (NIDDM) were studied for lipid peroxidation, antioxidant defences, and the maximum peroxidisable substrate in the cell membrane. Antioxidant defences are lowered in NIDDM, followed by significant rise in lipid peroxidation products. However, in the erythrocyte membrane, the total polyunsaturated peroxidisable lipids are lower than in normal erythrocytes which may be a causative factor affecting the survival of the cells.

Item Type:Article
Official URL/DOI:http://www.cellbiolint.org/cbi/default.htm
Uncontrolled Keywords:diabetic;lipid peroxidation;erythrocytes and cell
Subjects:Biochemistry,Cell and Molecular Signalling > Molecular Aspects-Insulin Resistence
Diabetes
Divisions:Department of Opthalmology
Department of Cell and Molecular Biology
Neonatal Diabetes
ID Code:298
Deposited By:INVALID USER
Deposited On:18 Dec 2009 09:56
Last Modified:18 Dec 2009 09:56

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