Mathangi, D C and Mohan, V and Namasivayam, A (1999) Effect of Cassava on motor co-ordination and neurotransmitter level in the albino rat. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 37 (1). pp. 57-60. ISSN 0278-6915
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Abstract
The root of Cassava, a tropical plant, is consumed in the tropics and has been attributed as the cause for various tropical neuropathies. This study aims to discover the neurotoxic effects of chronic cassava consumption of Indian origin and the effect of malnutrition. The assessment is based on the motor co-ordination and brain neurotransmitters in rats. Cassava consumption reduced the motor co-ordination, but the changes in neurotransmitter levels due to cassava consumption (except for 5HT in corpus striatum) was identical with malnutrition-induced changes, indicating that the toxicity of chronic cassava consumption (of Indian origin) is mainly due to the associated protein calorie malnutrition (PCM).
| Item Type: | Article |
|---|---|
| Official URL/DOI: | http://www.elsevier.com/wps/find/journaldescriptio... |
| Uncontrolled Keywords: | cassava; L-dopa; dopamine; 5-hydroxy tryptamine; 5-hydroxy indole acetic acid; homovanil- lic acid. |
| Subjects: | Genetics and Diabetes > Neurogenic Differentiation Factor 1(NEUROD1) Diabetology > Neuro Diabetology |
| Divisions: | Neonatal Diabetes Department of Diabetology |
| ID Code: | 234 |
| Deposited By: | INVALID USER |
| Deposited On: | 03 Dec 2009 15:12 |
| Last Modified: | 03 Dec 2009 15:12 |
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