Lack of association between serum sialic acid levels and retinopathy in Type 2 diabetic patients.

Deepa, R and Rema, M and Mohan, V (1998) Lack of association between serum sialic acid levels and retinopathy in Type 2 diabetic patients. Diabetes research and clinical practice, 41 (3). pp. 165-9. ISSN 0168-8227

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Abstract

Sialic acid, an acetylated derivative of neuraminic acid, is reported to be a marker of micro- and macrovascular complications in diabetic subjects. The purpose of this study was to investigate the association of serum sialic acid and diabetic retinopathy. Serum sialic acid levels were measured in healthy non-diabetic control subjects, Type 2 diabetic patients without retinopathy (No DR), Type 2 diabetic patients with non-proliferative diabetic retinopathy (NPDR) and Type 2 diabetic patients with proliferative diabetic retinopathy (PDR). There was no significant difference in the serum sialic acid levels between the study groups (controls, 2.1 mmol/l; No DR, 2.5 mmol/l; NPDR, 2.2 mmol/l and PDR, 2.3 mmol/l). These results suggest that there is no association between serum sialic acid levels and diabetic retinopathy.

Item Type:Article
Official URL/DOI:http://www.elsevier.com/wps/find/journaldescriptio...
Uncontrolled Keywords:Diabetes;Type 2 diabetic;retinopathy in Type 2 diabetic
Subjects:Diabetes > Diabetes Risk Factors
Diabetology > Retino Diabetology
Diabetology > Diabetes Mellitus Type 2
Divisions:Department of Opthalmology
Department of Diabetology
Department of Advanced Research Biochemistry
ID Code:224
Deposited By:INVALID USER
Deposited On:01 Dec 2009 16:03
Last Modified:01 Dec 2009 16:03

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