Kundu , P K and Moses, A and Chawla, R and Lachwani, D and Aterkar, S K and Choudhary, S R and Mohan, V (2019) Extrapancreatic Benefits and Pleiotropic Effects of Glimepiride: Value-Added Effects for Therapeutic Preference in Type 2 Diabetes Mellitus. Journal of the Association of Physicians, 67 . p. 33.
Glimepiride is a third-generation sulfonylurea (SU), which is a potential glucoselowering agent. It is widely used as monotherapy as well as combination therapy in the treatment of type 2 diabetes mellitus. Because of its safety, higher efficacy and low hypoglycemia potential, glimepiride is a preferred oral antidiabetic drug versus other SUs. Glimepiride has several extrapancreatic and pleiotropic benefits, which include insulin-sensitizing properties and anti-inflammatory, antioxidative and angiogenic effects. Additionally, the cardiovascular-neutral outcome of glimepiride makes it a preferred drug for the treatment of type 2 diabetes mellitus patients with cardiovascular disease or at risk. Here we will discuss various valueadded extrapancreatic and pleiotropic benefits of glimepiride.
|Uncontrolled Keywords:||Type 2 Diabetes Mellitus|
|Subjects:||Diabetology > Diabetes Mellitus Type 2|
|Divisions:||Department of Diabetology|
|Deposited By:||surendar radha|
|Deposited On:||05 Feb 2020 14:00|
|Last Modified:||05 Feb 2020 14:00|
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