IMPACT India: Insights for Insulin Therapy in Routine Clinical Practice

Mohan, V and Das, A K and Unnikrishnan, A G and Siddharth, N S and Ajay, K and Abdul , H Z and Kalra, S (2019) IMPACT India: Insights for Insulin Therapy in Routine Clinical Practice. Journal of the Association Physicians India . pp. 34-38.



Objective: Widely used in the management of diabetes, insulin therapy is influenced by several patient preferences and physician choices. This article reports the findings of the IMPACT survey, designed to assess insights on various factors which influence the choice of insulin therapy in India. Methods: We administered a questionnaire which focused on the practice and patient profiles and the preferred regimens in specific clinical situations using a case scenario. Respondents were asked about preferred insulin regimens for various phases of life, comorbid conditions, dietary choices and psychological factors. Results: Overall, 314 doctors participated in the survey. Majority were general physicians (51%) and diabetologists (37%). In clinical practice, the most preferred regimens included premix insulin BD in adults (59%) and elderly (53%), and basal bolus therapy in pregnant women (>47%) and in acute illness (62%). Both regimens were equally preferred for symptomatic patients (41% basal bolus and 38% premix insulin) and those with renal or hepatic failure (36% each). Premix insulin was preferred for patients with high carbohydrate intake (73%) while basal bolus was preferred for patients with variable meal timings (39%) and in pronounced postprandial glucose excursions (45%). Insulin co-formulation and high-mix insulins were not a part of the survey questionnaire. Summary: Indian physicians exercise logic in the choice of insulin regimens. Preference is based on patient characteristics including glucophenotype, dietary patterns, psychosocial needs, clinical situations, and comorbid conditions.

Item Type:Article
Official URL/DOI:
Uncontrolled Keywords:Insulin Therapy; Clinical practice
Divisions:Department of Diabetology
ID Code:1120
Deposited By:surendar radha
Deposited On:06 Sep 2019 12:03
Last Modified:06 Sep 2019 12:03

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