Diabetes in South Asians: Phenotype, Clinical Presentation, and Natural History

Unnikrishnan, R and Gupta, P and Mohan, V (2018) Diabetes in South Asians: Phenotype, Clinical Presentation, and Natural History. Current Diabetes Reports, 18 (6). ISSN 1534-4827



Purpose of Review South Asia is one of the epicenters of the global diabetes pandemic. Diabetes in south Asians has certain peculiar features with respect to its pathophysiology, clinical presentation, and management. This review aims to summarize some of the recent evidence pertaining to the distinct diabetes phenotype in south Asians. Recent Findings South Asia has high incidence and prevalence rates of diabetes. The progression from “pre-diabetes” to diabetes also occurs faster in this population. Pancreatic beta cell dysfunction seems to be as important as insulin resistance in the pathophysiology of diabetes in south Asians. Recent evidence suggests that the epidemic of diabetes in south Asia is spreading to rural areas and to less affluent sections of society. Summary Diabetes in south Asians differs significantly from that in white Caucasians, with important implications for prevention, diagnosis, and management.

Item Type:Article
Official URL/DOI:http://dx.doi.org/10.1007/s11892-018-1002-8
Uncontrolled Keywords:Diabetes; Pre-diabetes; South Asians; Phenotype; Incidence; Prevalence
Divisions:Department of Diabetology
ID Code:1095
Deposited By:surendar radha
Deposited On:25 Jul 2018 11:12
Last Modified:25 Jul 2018 11:12

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